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neweastbio@126.com
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| 价格 | ￥4800.00 |
| 品牌 | NewEast Biosciences  |
| 产地 | 中国 武汉 |
| 货号 | 26922 |
| 规格 | 30μl |
| 说明书 | 说明书下载 |
Active Rab35 GTP [26922]
[30 µL]
| Catalog Number: 26922 |
| Gene Symbol: RAB35 |
| Description: Anti Active Rab35 Mouse Monoclonal Antibody |
| Background: The Rab family of GTPases regulates eukaryotic vesicular membrane traffic. Rab35 is with both plasma membrane and endosomal localization, and has been implicated in diverse processes that include T-cell receptor recycling, oocyte yolk protein recycling and cytokinesis. Rab35 regulates neurite outgrowth in neuronal-like cells, and can induce protrusions. |
| Immunogen: Recombinant full length protein of active Rab35 |
| Applications: IP, IHC, IF |
| Recommended Dilutions: 1 µg for ~2 mg total cellular proteins for IP 1:100 dilution for IHC, IF |
| Concentration: 1 mg/ml |
| Host: mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti active Rab35 antibody recognizes active Rab35 proteins of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Immunoprecipitation/Western blot: |
 |
Rab35 activation assay. Purified full-length Rab35 proteins were immunoprecipitated after treated with GDP (lane 1) orGTPγS (lane 2). Immunoprecipitation was done with the anti active Rab35 monoclonal antibody (Cat. No. 26922). Immunoblot was with an anti Rab35 polyclonal antibody (Cat. No. 21078). |
| Related Products | |||
| Catalog# | Name | Size | Price |
| 82801 | Rab35 Activation Assay Kit | 20 assays | ￥6800 |
| 26922 | Active Rab35-GTP Monoclonal Antibody | 30 μL | ￥4800 |
| 21078 | Anti Rab35 Rabbit Polyclonal Antibody | 100 μL | ￥2600 |
| Publications: |
| 1. VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors Hepatology Volume 61, Issue 1, pages 361–374, January 2015 |
| 2. Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance Endocrinology. 2014 Sep;155(9):3315-28 |
